A total of 3 % of active substance is excreted in urine as unchanged active compound. Tapentadol is Also metabolised to N-desmethyl tapentadol (13 %) by CYP2C9 and CYP2C19 and also to hydroxy tapentadol (two %) by CYP2D6, that happen to be even further metabolised by conjugation. Therefore, Energetic compound https://tupeniw179bac7.wssblogs.com/profile