You will find a launch of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors inside the dorsal horn to decrease afferent soreness transmission and produce analgesia. As a result, medicines like clonidine that concentrate on alpha-two receptors can affect the transmission of soreness. This info just https://hilaryt739ofv5.iamthewiki.com/user