You will find there's release of norepinephrine from your descending inhibitory bulbospinal neurons that binds to alpha-two-receptors inside the dorsal horn to minimize afferent pain transmission and generate analgesia. For that reason, medications like clonidine that target alpha-two receptors can affect the transmission of suffering. Jun 10, 2024 · https://socialicus.com/story5219438/detailed-notes-on-onolidine